Hemophilia: Causes, Symptoms, & Treatment

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Hemophilia: Causes, Symptoms, & Treatment

Hemophilia is a rare disorder in which your blood does not clot properly because it lacks blood clotting factors. If you have hemophilia, then you may bleed for a much longer time than you would do in a normal condition. Small cuts do not cause much of a problem but deep cuts can cause severe deep internal bleeding especially in your knees, ankles, and elbows. The internal bleeding can cause severe damage to your organs and tissues and may be life-threatening. Hemophilia is an inherited disorder (genetic). Treatment includes the replacement of the clotting factor when reduced. We will discuss the causes and symptoms of hemophilia. Treatment of hemophilia will also be discussed later in the section.

Causes of Hemophilia

When blood clotting factors decrease in your body, your injuries get severe automatically.

Basically, there are 2 types of hemophilia:

  • Acquired hemophilia

About 30 percent of people are affected by acquired hemophilia. In this type, a mutation in your genes causes hemophilia. This is a less common phenomena than inherited hemophilia.

  • Inherited hemophilia

In this type of hemophilia, a faulty gene is located on chromosome X of the mother. In this, a mother can be a carrier and most often pass it to boys. Mothers do not feel any clear symptom or sign but can experience bleeding symptoms if clotting factors are moderately decreased. This is the most common phenomena amongst people who are affected by hemophilia.

Symptoms of Hemophilia

If your clotting factors are severely decreased, then you may experience bleeding.

Some signs and symptoms of hemophilia include:

  • Unexplained and excessive bleeding
  • Large or deep bruises
  • Unusual bleeding after vaccinations
  • Pain, swelling or tightness in joints
  • Blood in urine or stool
  • Nosebleeds without a known cause
  • In infants, unexplained irritability

Bleeding in the brain

A single bump on your head can lead to severe bleeding if you are affected with hemophilia. Some signs and symptoms of head bleeding include:

  • Painful, prolonged headache
  • Repeated vomiting
  • Sleepiness
  • Double vision
  • Sudden weakness
  • Convulsions or seizures

These are some of the signs and symptoms of hemophilia.

Treatment of Hemophilia

  • Haemophilia is treated with replacement therapy, in which the clotting factors are replaced and is put into the blood through injection and intravenously. Clotting factors may be taken from human blood. Synthetically produced factors are called recombinant clotting factors.
  • Recombinant clotting factors are now considered as a choice as it reduces the risk of transmitting infections that are carried out in human blood.
  • Some patients may require regular replacements in order to prevent bleeding. This is called prophylactic therapy. This is mainly considered for people with hemophilia A infection.
  • Demand therapy is recommended for people who bleed and bleed uncontrollably.
  • Damage to joints, muscles, and body parts can occur if the treatment is delayed.
  • Other treatments for mild hemophilia A include desmopressin, a man-made hormone that stimulates the release of stored factor VIII, and antifibrinolytic medicines that prevent the clot from breaking down.

In the future, gene therapies may also be available.

Now, we have discussed the causes and symptoms of hemophilia along with the treatment of hemophilia. For more health and beauty-related tips, follow this section closely.